What is the new method of alcohol abuse in dopamine alcoholism?

Scientists say, "They found a group of neurons in their brains. These neurons have an impact on people's drinking, which may eventually lead people to discover ways to cure alcohol and other addictions."

The results of this study have been published in the Journal of Neuroscience by researchers at the Texas A&M University School of Health Sciences.

The study concluded that the dorsal striatum of the brain is the area in which the brain controls the target-directed behavior, and alcohol causes a sustained change in the morphology of neurons in this part of the brain. "In addition, we found that these changes only occur in a subset of neurons, which actively control the reward and strengthening mechanisms of drug abuse."

The authors of the study looked forward to the drug treatment of alcoholism: in the end, we found that inhibiting the activity of the receptor can control drinking behavior.

The co-author of the animal study and researchers at the University of California, San Francisco found that alcohol changes the physical structure of medium-sized spinous processes (the main type of cells in the striatum).

These neurons can promote or inhibit the performance of specific behaviors because of D1 or D2 dopamine receptors. D1 neurons are often referred to as part of the brain's "go to do" pathway, while D2 neurons are part of the "do not do" pathway.

The team found that periodic drinking behaviors act on D1 neurons, making the brain more exciting. Therefore, their activation requires only a small amount of stimulation.

Wang Jun, the first author and assistant professor of neuroscience and experimental therapy, explained: "If these neurons are excited, you will want to drink and craving for drinking."

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